Reconstruction and Prevention: Nanotechnology and Tissue Engineering Approaches for Cancer Patients
DOI:
https://doi.org/10.47611/jsr.v13i3.2637Keywords:
Nanotechnology, Cancer, Prevention, Reconstruction, Environmental RemediationAbstract
Cancer is a complex disease responsible for one-in-sixth deaths. Various environmental contaminants: heavy metals, synthetic organic dyes, asbestos, polychlorinated biphenyls (PCBs), and polycyclic aromatic hydrocarbons are carcinogenic in nature. This paper investigates the potential of nanotechnology in tissue repair and cancer prevention by environmental remediation of carcinogenic pollutants. Solid lipid nanoparticles, including liposomes, are promising candidates for targeted drug delivery and tissue engineering applications. These nanocarriers can be engineered to selectively bind to diseased cells, delivering therapeutic drugs and potentially facilitating tissue repair processes. The development of those nanoparticles can benefit from combining it with Artificial Intelligence, i.e. AI can help to determine the shape and the size of the solid lipid nanoparticles targeting damaged tissues, and more importantly their biocompatibility to prevent further harm to the already damaged tissues. Molecular imaging techniques used for early detection and monitoring of carcinogenic cells can identify areas of damaged tissue with high sensitivity. This information can then be used to guide the targeted delivery of nanocarriers to the tumor site. Beyond drug delivery and tissue engineering applications, nanotechnology holds potential for cancer prevention strategies by environmental remediation of known carcinogenic pollutants. For example, ferric oxide nanoparticles have been shown to eliminate cadmium and arsenic from toxic substances.
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Aguilar M., Sáez J., Lloréns M., Soler A., Ortuño J. F. Nutrient removal and sludge production in the coagulation-flocculation process. Water Research . 2002;36(11):2910–2919. doi: 10.1016/S0043-1354(01)00508-5
Amuda O. S., Amoo I. A. Coagulation/flocculation process and sludge conditioning in beverage industrial wastewater treatment. Journal of Hazardous Materials . 2007;141(3):778–783. doi: 10.1016/J.JHAZMAT.2006.07.044
Ayenigbara I. O. (2023). Risk-Reducing Measures for Cancer Prevention. Korean journal of family medicine, 44(2),
–86. https://doi.org/10.4082/kjfm.22.0167
Bansal P., Chaudhary G. R., Mehta S. K. Comparative study of catalytic activity of ZrO2 nanoparticles for sonocatalytic and photocatalytic degradation of cationic and anionic dyes. Chemical Engineering Journal . 2015;280:475–485. doi: 10.1016/j.cej.2015.06.039
Chemotherapy side effects. CancerCare. (n.d.). https://www.cancercare.org/chemo-side-effects?gad_source=1&gclid=CjwKCAjw88yxBhBWEiwA7cm6pbhwuWVaPb6GmO8AWEqjs-OyK1vbjRf0zq0eUf7xt2PZiaj-zZkOpRoCfEYQAvD_BwE
Diesel pollution is a deadly problem in the United States. (2022, January 20). Clean Air Task Force. Retrieved March 29, 2024, from https://www.catf.us/2022/01/diesel-pollution-deadly-problem-united-states/
Govindan, B., Sabri, M. A., Hai, A., Banat, F., & Haija, M. A. (2023). A Review of Advanced Multifunctional
Magnetic Nanostructures for Cancer Diagnosis and Therapy Integrated into an Artificial Intelligence
Approach. Pharmaceutics, 15(3), 868. https://doi.org/10.3390/pharmaceutics15030868
Homaeigohar S., Zillohu A., Abdelaziz R., Hedayati M., Elbahri M. A novel nanohybrid nanofibrous adsorbent for water purification from dye pollutants. Materials . 2016;9(10):p. 848. doi: 10.3390/ma9100848
How Does Artificial Intelligence Work? (2021, August 9). CSU Global. Retrieved March 29, 2024, from https://csuglobal.edu/blog/how-does-ai-actually-work
Iwuozor K. O. Prospects and challenges of using coagulation-flocculation method in the treatment of effluents. Advanced Journal of Chemistry-Section A . 2019;2:105–127. doi: 10.29088/sami/ajca.2019.2.105127
Jin, C., Wang, K., Oppong-Gyebi, A., & Hu, J. (2020). Application of Nanotechnology in Cancer Diagnosis and
Therapy - A Mini-Review. International journal of medical sciences, 17(18), 2964–2973.
https://doi.org/10.7150/ijms.49801
Moniri Javadhesari, S., Koohi, M., & Jabraili, M. (2022). Nanomaterials: Applications in Regeneration of
Damaged Tissues. Advanced Ceramics Progress, 8(4), 1-14. doi: 10.30501/acp.2022.356039.1100
Mosleh-Shirazi, S., Abbasi, M., Moaddeli, M. R., Vaez, A., Shafiee, M., Kasaee, S. R., Amani, A. M., & Hatam, S.
(2022). Nanotechnology Advances in the Detection and Treatment of Cancer: An Overview.
Nanotheranostics, 6(4), 400–423. https://doi.org/10.7150/ntno.74613
Ng, C., & Chang, Y. (2020, January 28). Penn nanoparticles are less toxic to T cells engineered for cancer immunotherapy | Penn Today. Penn Today. Retrieved March 29, 2024, from https://penntoday.upenn.edu/news/nanoparticle-delivery-system-brings-less-toxic-approach-car-t-immunotherapy
Parsa N. (2012). Environmental factors inducing human cancers. Iranian journal of public health, 41(11), 1–9.
Perán, M., García, M. A., Lopez-Ruiz, E., Jiménez, G., & Marchal, J. A. (2013). How Can Nanotechnology Help to
Repair the Body? Advances in Cardiac, Skin, Bone, Cartilage and Nerve Tissue Regeneration. Materials
(Basel, Switzerland), 6(4), 1333–1359. https://doi.org/10.3390/ma6041333
Poznyak T., Bautista G. L., Chaírez I., Córdova R. I., Ríos L. E. Decomposition of toxic pollutants in landfill leachate by ozone after coagulation treatment. Journal of Hazardous Materials . 2008;152(3):1108–1114. doi: 10.1016/J.JHAZMAT.2007.07.098
Roser, M., & Ritchie, H. (2024, March 12). Cancer. Our World in Data. https://ourworldindata.org/cancer#:~:text=About%20ten%20million%20people%20die,the%20largest%20health%20problems%20globally.
Roy, A., Sharma, A., Yadav, S., Jule, L. T., & Krishnaraj, R. (2021). Nanomaterials for Remediation of Environmental Pollutants. Bioinorganic chemistry and applications, 2021, 1764647. https://doi.org/10.1155/2021/1764647
Singh P. K. T. R., Vats S., Kumar D., Tyagi S. Nanomaterials use in wastewater treatment. Proceedings of the International Conference on Nanotechnology and Chemical Engineering; 2012; Bangkok, Thailand
Tan K. B., Vakili M., Horri B. A., Poh P. E., Abdullah A. Z., Salamatinia B. Adsorption of dyes by nanomaterials: recent developments and adsorption mechanisms. Separation and Purification Technology . 2015;150:229–242. doi: 10.1016/j.seppur.2015.07.009
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Copyright (c) 2025 Shiven Murthy; Kristina Lilova, Virgel Torremocha , Jothsna Kethar
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