Development of a Tetracycline Resistant Strain of E. coli Sensitive to Ultraviolet Radiation

Abstract

Multidrug resistance bacteria pose a significant threat to human health and the efforts of the medical community.  Given our reliance on antibiotics for therapeutic treatment of bacterial infections it is imperative to understand the mechanism by which bacteria develop antibiotic resistance.  In the present report we develop a strain of Escherichia coli capable of resisting high levels of tetracycline and other protein synthesis inhibitors.  Furthermore the tetracycline resistant strain is approximately 1/3^rd in length and is sensitive to UV radiation.