Molecular predisposition and environmental factors in development of diffuse large B cell lymphoma

Abstract

Due to increased amounts of industrial and food related carcinogens, rising rates of cancers such as Diffuse Large B Cell Lymphoma pose a serious threat to the wellbeing of people. Although cases of Diffuse Large B Cell Lymphoma (DLBCL) are found globally, a staggering majority of the cases are found in developed nations, such as the United States and United Kingdom. Current research on DLBCL mostly focuses on potential cures rather than on preventative measures individuals can take. Additionally, DLBCL, a type of non-Hodgkin's Lymphoma, is a diffused cancer. This means the cancerous cells travel all over the body through the lymphatic system. DLBCL has one of the highest rates of metastasis because the lymphatic system is connected to all organs in the body. After in-depth research into the impacts of genetic predisposition, environmental causation, and lifestyle habits on DLBCL lymphatogenesis, a research-backed map was created to help guide individuals with DLBCL genetic predisposition, who are exposed to certain carcinogens through food and drink, and the average inhabitant of developed countries to living lives that are preventative to DLBCL. This paper concludes that factors such as genetic testing,  dietary changes including reduced consumption of bovine milk and edible dyes, and limited exposure to certain environmental carcinogens such as benzene all allow individuals to be proactive about their health. This research allows individuals who are concerned about their chances of developing cancer to understand and employ preventative measures into their lives, effectively preventing, stabilizing, or halting the development of any DLBCL.