Photobiomodulation: A Review

Authors

  • Tara Peddi Fusion Global Academy

DOI:

https://doi.org/10.47611/jsrhs.v13i3.7083

Keywords:

photobiomodulation, green light, chronic pain, nociception, low level light therapy

Abstract

Photobiomodulation (PBM), is a low-level light therapy at wavelengths between 400 to 1100 nanometers. It includes the green section of the visible light spectrum (495 to 570 nm) that has attracted substantial attention for the management of conditions such as pain. The use of light exposure for medical treatment or phototherapy has a long history. Niels Ryberg Finsen, a Nobel laureate, reported using ultraviolet light to cure lupus vulgaris and red-light to treat smallpox in the late 1800s [1]. Using phototherapy in the form of light has recently received more attention. Various wavelengths of light have treated a diverse spectrum of ailments including psoriasis, seasonal affective disorder, neonatal jaundice, circadian rhythm disruptions and acne [2]. The applications of phototherapy are broad, ranging from pain control to promoting the healing of wounds, tendon injuries, nerve injuries and arthritis. A comprehensive review of the literature is presented in this review article.

Downloads

Download data is not yet available.

References or Bibliography

References

Møller, K. I., Kongshoj, B., Philipsen, P. A., Thomsen, V. O., & Wulf, H. C. (2005). How Finsen's light cured lupus vulgaris. Photodermatology, photoimmunology & photomedicine, 21(3), 118–124. https://doi.org/10.1111/j.1600-0781.2005.00159.x

Cheng, K., Martin, L. F., Calligaro, H., Patwardhan, A., & Ibrahim, M. M. (2022). Case Report: Green Light Exposure Relieves Chronic Headache Pain in a Colorblind Patient. Clinical medicine insights. Case reports, 15, 11795476221125164. https://doi.org/10.1177/11795476221125164

Avci, P., Gupta, A., Sadasivam, M., Vecchio, D., Pam, Z., Pam, N., & Hamblin, M. R. (2013). Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring. Seminars in cutaneous medicine and surgery, 32(1), 41–52.

Heiskanen, V., & Hamblin, M. R. (2018). Photobiomodulation: lasers vs. light emitting diodes?. Photochemical & photobiological sciences: Official journal of the European Photochemistry Association and the European Society for Photobiology, 17(8), 1003–1017. https://doi.org/10.1039/c8pp90049c

de Freitas, L. F., & Hamblin, M. R. (2016). Proposed Mechanisms of Photobiomodulation or Low-Level Light Therapy. IEEE journal of selected topics in quantum electronics: a publication of the IEEE Lasers and Electro-optics Society, 22(3), 7000417. https://doi.org/10.1109/JSTQE.2016.2561201

Chung, H., Dai, T., Sharma, S. K., Huang, Y. Y., Carroll, J. D., & Hamblin, M. R. (2012). The nuts and bolts of low-level laser (light) therapy. Annals of biomedical engineering, 40(2), 516–533. https://doi.org/10.1007/s10439-011-0454-7

González-Muñoz, A., Cuevas-Cervera, M., Pérez-Montilla, J. J., Aguilar-Núñez, D., Hamed-Hamed, D., Aguilar-García, M., Pruimboom, L., & Navarro-Ledesma, S. (2023). Efficacy of Photobiomodulation Therapy in the Treatment of Pain and Inflammation: A Literature Review. Healthcare (Basel, Switzerland), 11(7), 938. https://doi.org/10.3390/healthcare11070938

Liebert, A., Bicknell, B., Laakso, E. L., Heller, G., Jalilitabaei, P., Tilley, S., Mitrofanis, J., & Kiat, H. (2021). Improvements in clinical signs of Parkinson's disease using photobiomodulation: a prospective proof-of-concept study. BMC neurology, 21(1), 256. https://doi.org/10.1186/s12883-021-02248-y

Nelli, Amanda H, et al. “Green Light-Based Analgesia – Novel Nonpharmacological Approach to Fibromyalgia Pain: A Pilot Study.” Pain Physician Journal, July 2023, Green Light-Based Analgesia – Novel Nonpharmacological Approach to Fibromyalgia Pain: A Pilot Study.

Rikard SM, Strahan AE, Schmit KM, Guy GP Jr. Chronic Pain Among Adults — United States, 2019–2021. MMWR Morb Mortal Wkly Rep 2023;72:379–385. DOI: http://dx.doi.org/10.15585/mmwr.mm7215a1.

Tracey, W. Daniel. “Nociception.” Current Biology, vol. 27, no. 4, Feb. 2017, https://doi.org/10.1016/j.cub.2017.01.037

Armstrong, Scott A. “Physiology, Nociception.” StatPearls [Internet]., U.S. National Library of Medicine, 1 May 2023, www.ncbi.nlm.nih.gov/books/NBK551562/

Cervero F (2012). Understanding Pain: Exploring the Perception of Pain. Cambridge, Mass.: MIT Press. pp. Chapter 1. ISBN 9780262305433. OCLC 809043366

Turk, D. C., & Okifuji, A. (2020, September 21). Pain Terms and Taxonomies of Pain. Anesthesia Key. Retrieved April 3, 2024, from https://aneskey.com/pain-terms-and-taxonomies-of-pain/

Raffaeli, W., & Arnaudo, E. (2017). Pain as a disease: an overview. Journal of pain research, 10, 2003–2008. https://doi.org/10.2147/JPR.S138864

Luo F, Li M, Florence C. State-Level Economic Costs of Opioid Use Disorder and Fatal Opioid Overdose — United States, 2017. MMWR Morb Mortal Wkly Rep 2021;70:541–546. DOI: http://dx.doi.org/10.15585/mmwr.mm7015a1external icon

El Geziry, A., Toble, Y., Al Kadhi, F., & Pervaiz and Mohammad Al Nobani, M. (2018). Non-Pharmacological Pain Management. IntechOpen. doi: 10.5772/intechopen.79689

Serrage, H. Heiskanen, V., Palin, W. M., Cooper, P. R., Milward, M. R., Hadis, M., & Hamblin, M. R., (2019). Under the spotlight: mechanisms of photobiomodulation concentrating on blue and green light. Photochemical & photobiological sciences: Official journal of the European Photochemistry Association and the European Society for Photobiology, 18(8), 1877–1909. https://doi.org/10.1039/c9pp00089e

Miller, H., Reed, K., & Ibrahim, M. (2021). Green Light Therapy: Pilot Intervention to Improve Anxiety in Pregnant Women with Opioid Use Disorder. American Journal of Obstetrics & Gynecology, 228(1). https://doi.org/10.1016/j.ajog.2022.11.275

Takemura, Y., Kido, K., Kawana, H., Yamamoto, T., Sanuki, T., & Mukai, Y. (2021). Effects of Green Color Exposure on Stress, Anxiety, and Pain during Peripheral Intravenous Cannulation in Dental Patients Requiring Sedation. International journal of environmental research and public health, 18(11), 5939. https://doi.org/10.3390/ijerph18115939

Noseda, R., Bernstein, C. A., Nir, R. R., Lee, A. J., Fulton, A. B., Bertisch, S. M., Hovaguimian, A., Cestari, D. M., Saavedra-Walker, R., Borsook, D., Doran, B. L., Buettner, C., & Burstein, R. (2016). Migraine photophobia originating in cone-driven retinal pathways. Brain: a journal of neurology, 139(Pt 7), 1971–1986. https://doi.org/10.1093/brain/aww119

Martin, L. F., Patwardhan, A. M., Jain, S. V., Salloum, M. M., Freeman, J., Khanna, R., Gannala, P., Goel, V., Jones-MacFarland, F. N., Killgore, W. D., Porreca, F., & Ibrahim, M. M. (2021). Evaluation of green light exposure on headache frequency and quality of life in migraine patients: A preliminary one-way cross-over clinical trial. Cephalalgia: an international journal of headache, 41(2), 135–147. https://doi.org/10.1177/0333102420956711

Ibrahim, M. M., Patwardhan, A., Gilbraith, K. B., Moutal, A., Yang, X., Chew, L. A., Largent-Milnes, T., Malan, T. P., Vanderah, T. W., Porreca, F., & Khanna, R. (2017). Long-lasting antinociceptive effects of green light in acute and chronic pain in rats. Pain, 158(2), 347–360. https://doi.org/10.1097/j.pain.0000000000000767

Published

08-31-2024

How to Cite

Peddi, T. (2024). Photobiomodulation: A Review. Journal of Student Research, 13(3). https://doi.org/10.47611/jsrhs.v13i3.7083

Issue

Section

HS Review Articles