Review of Acute Myeloid Leukemia
DOI:
https://doi.org/10.47611/jsrhs.v13i3.7072Keywords:
Acute Myeloid Leukemia (AML), Review JournalAbstract
Leukemia is a type of blood cancer, which caused 474,519 new cases recorded worldwide in 2020 with an age-standardized incidence rate of 5.4 in 100,000 and 311,594 linked deaths were reported in terms of mortality (Huang et al., 2022). Acute myeloid leukemia (AML) is one of the 4 subtypes in leukemia and it contributes to roughly 31% of all leukemia cases (Cancer.Net, 2019). The purpose of this paper is to conduct a general overview of the classification, pathogenesis, symptoms, diagnosis, treatments and the current research of AML.
Downloads
References or Bibliography
Abdullah, M., El-Zine, Y., Alhadi, A., Ishak A., & Alshamahy H. (2021) Prevalence of
Different Types of Leukemia and Associated Factors among Children with Leukemia in Children’s Cancer Units at Al-Kuwait Hospital, Sana’a City: A Cross-Sectional Study.
Global Journal of Pediatrics & Neonatal Care.
Acute Myeloid Leukemia - Ask Hematologist | Understand Hematology. (2016, April 13).
Askhematologist.com.
https://askhematologist.com/acute-myeloid-leukemia-aml/
Acute myeloid leukemia (AML) subtypes and prognostic factors. (n.d.). American Cancer
Acute myelogenous leukemia - Diagnosis and treatment - Mayo Clinic. (2022, September
Acute myeloid leukemia treatment. (2023b, September 8). National Cancer Institute.
https://www.cancer.gov/types/leukemia/patient/adult-aml-treatment-pdq
Blood smear. (n.d.).
https://medlineplus.gov/lab-tests/blood-smear/
Brunangelo Falini. (2023). NPM1‐mutated acute myeloid leukemia: New pathogenetic
and therapeutic insights and open questions. American Journal of Hematology,
(9), 1452–1464.
https://doi.org/10.1002/ajh.26989
Box, J. K., Paquet, N., Adams, M. N., Boucher, D., Bolderson, E., O’Byrne, K. J., &
Richard, D. J. (2016). Nucleophosmin: from structure and function to disease development. BMC Molecular Biology, 17(1). https://doi.org/10.1186/s12867-016-0073-9
Cancer.net. (2019, February 28). Leukemia - Acute Myeloid - AML - Statistics.
Cancer.net.
https://www.cancer.net/cancer-types/leukemia-acute-myeloid-aml/statistics
Cooper, J. N., & Young, N. S. (2017). Clonality in context: hematopoietic clones in their
marrow environment. Blood, 130(22), 2363–2372. https://doi.org/10.1182/blood-2017-07-794362
Crans, H., & Sakamoto, K. (2001). Transcription factors and translocations in lymphoid
and myeloid leukemia. Leukemia, 15(3), 313–331. https://doi.org/10.1038/sj.leu.2402033
De Kouchkovsky, I., & Abdul-Hay, M. (2016). ‘Acute myeloid leukemia: a
comprehensive review and 2016 update.’ Blood Cancer Journal, 6(7), e441. https://doi.org/10.1038/bcj.2016.50
DiNardo, C. D., Erba, H. P., Freeman, S., & Wei, A. H. (2023). Acute myeloid leukaemia.
The Lancet, 401(10393), 2073–2086.
https://doi.org/10.1016/s0140-6736(23)00108-3
Dong, J., Qi, M., Wang, S., & Yuan, X. (2020b). DINTD: Detection and Inference of
tandem duplications from short sequencing reads. Frontiers in Genetics, 11. https://doi.org/10.3389/fgene.2020.00924
Fedorov, K., Maiti, A., & Konopleva, M. (2023). Targeting FLT3 mutation in acute
myeloid leukemia: Current strategies and future directions. Cancers, 15(8), 2312. https://doi.org/10.3390/cancers15082312
Gilliland, D. G., & Griffin, J. D. (2002b). The roles of FLT3 in hematopoiesis and
leukemia. Blood, 100(5), 1532–1542.
https://doi.org/10.1182/blood-2002-02-0492
Hasserjian, R. P. (2013). Acute myeloid leukemia: advances in diagnosis and
classification. International Journal of Laboratory Hematology, 35(3), 358–366. https://doi.org/10.1111/ijlh.12081
Huang, J., Chan, S. C., Ngai, C. H., Lok, V., Zhang, L., Lucero‐Prisno, D. E., Xu, W.,
Zheng, Z., Elcarte, E., Withers, M., & Wong, M. C. (2022). Disease Burden, Risk Factors, and Trends of Leukemia: A Global analysis. Frontiers in Oncology, 12. https://doi.org/10.3389/fonc.2022.904292
Hwang S. M. (2020). Classification of acute myeloid leukemia. Blood research, 55(S1),
S1–S4.
https://doi.org/10.5045/br.2020.S001
Kampen, K. R. (2011). The discovery and early understanding of leukemia. Leukemia
Research, 36(1), 6–13.
https://doi.org/10.1016/j.leukres.2011.09.028
Kassahun, W., Tesfaye, G., Bimerew, L. G., Fufa, D., Adissu, W., & Yemane, T. (2020)
Prevalence of Leukemia and Associated Factors among Patients with Abnormal Hematological Parameters in Jimma Medical Center, Southwest Ethiopia: A Cross-Sectional Study. Hindawi.
https://downloads.hindawi.com/journals/ah/2020/2014152.pdf
Kiyoi, H., Kawashima, N., & Ishikawa, Y. (2019). FLT3 mutations in acute myeloid
leukemia: Therapeutic paradigm beyond inhibitor development. Cancer Science, 111(2), 312–322.
https://doi.org/10.1111/cas.14274
Knottenbelt, D. C. (2015c). Tumours of the cardiovascular system. In Elsevier eBooks
(pp. 512–543).
https://doi.org/10.1016/b978-0-7020-4266-9.00030-1
Leukemia - Acute myeloid - AML - latest research. (2022, April 28). Cancer.Net.
Normal peripheral blood smear. (2008). Imagebank.hematology.org.
https://imagebank.hematology.org/imageset/668/normal-peripheral-blood-smear
Ramaiah, L., Bounous, D. I., & Elmore, S. A. (2013b). Hematopoietic system. In Elsevier
eBooks (pp. 1863–1933).
https://doi.org/10.1016/b978-0-12-415759-0.00050-9
Shumilov, E., Flach, J., Kohlmann, A., Banz, Y., Bonadies, N., Fiedler, M., Pabst, T., &
Bacher, U. (2018). Current status and trends in the diagnostics of AML and MDS. Blood Reviews, 32(6), 508–519.
https://doi.org/10.1016/j.blre.2018.04.008
Skopek, R., Palusińska, M., Kaczor-Keller, K., Pingwara, R., Papierniak-Wyglądała, A.,
Schenk, T., Lewicki, S., Zelent, A., & Szymański, Ł. (2023). Choosing the Right Cell Line for Acute Myeloid Leukemia (AML) Research. International journal of molecular sciences, 24(6), 5377.
https://doi.org/10.3390/ijms24065377
Steffen, B., Müller‐Tidow, C., Schwäble, J., Berdel, W. E., & Serve, H. (2005). The
molecular pathogenesis of acute myeloid leukemia. Critical Reviews in Oncology/Hematology, 56(2), 195–221.
https://doi.org/10.1016/j.critrevonc.2004.10.012
Tefferi, A., & Letendre, L. (2012). Going Beyond 7 + 3 Regimens in the Treatment of
Adult Acute Myeloid Leukemia. Journal of Clinical Oncology, 30(20), 2425–2428.
https://doi.org/10.1200/jco.2011.38.9601
Tests for acute myeloid leukemia (AML). (n.d.). American Cancer Society.
The Cancer Genome Atlas Research Network. (2013). Genomic and Epigenomic
Landscapes of Adult De Novo Acute Myeloid Leukemia. New England Journal of Medicine, 368(22), 2059–2074.
https://doi.org/10.1056/nejmoa1301689
Yao, Y., Lin, X., Wang, C., Gu, Y., Jin, J., Zhu, Y., & Wang, H. (2023). Identification of a
novel NPM1 mutation in acute myeloid leukemia. Experimental Hematology &
Oncology, 12(1).
Published
How to Cite
Issue
Section
Copyright (c) 2024 Yinghao Liu
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Copyright holder(s) granted JSR a perpetual, non-exclusive license to distriute & display this article.
