Personalized Medicine In Chron's Disease

Divyasree Prem Sankar; Rajagopal Appavu

doi:10.47611/jsrhs.v13i2.6780

Authors

Divyasree Prem Sankar Zionsville High School
Rajagopal Appavu

DOI:

https://doi.org/10.47611/jsrhs.v13i2.6780

Keywords:

Inflammatory diseases, Gene therapy, Personalized Medicine, CRISPR-CAS9, Gene Editing

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Abstract

Crohn's disease is an autoimmune disease that has no complete cure. Although the disease has no cure, there are many different ways to treat it. The cause of Crohn's disease is not entirely known yet. However, researchers suspect that a mutation in the NOD2 gene causes Crohn's, and they have found many statistics to prove that the Nucleotide Binding Oligomerization DomainCcontaining 2 (NOD2) is the reason for Crohn's. Many other genes contribute to the cause of Crohn’s, but for this research paper, NOD2 is the main focus. NOD2 is a crucial gene in the immune system; because of its vital role, a mutation in this gene can have many effects. This paper will first discuss Crohn's and why NOD2 is essential. A popular and emerging topic in the field of medicine is personalized medicine. Personalized medicine is using or changing an individual's gene to help treat or cure the disease the individual is fighting. This paper will explore the details of personalized medicine and its different types. Personalization transforms the field of healthcare since perspectives are changing. Instead of everyone getting the same medication no matter how their body reacts to it, personalized medicine can provide a unique and personal treatment for the disease. To conclude, the paper will address and analyze the effect of personalized medicine on Crohn's disease and its impact.

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References or Bibliography

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ALL ABOUT CHRONS: https://medlineplus.gov/genetics/condition/crohn-disease/#:~ :text=The%20causes%20of%20Crohn%20disease,involved%20in%20immune%20system%20function

EFFECTS OF CHRONS: https://www.niddk.nih.gov/health-information /digestive-diseases/crohns-disease/definition-facts

ENDOSCOPY: https://www.nhs.uk/conditions/endoscopy/

HOW CROHN’S IS DIAGNOSED: https://www.niddk.nih.gov/health-infor mation/digestive-diseases/crohn's-disease/diagnosis#:~:text=of%20digestive%20diseases.-,Intestinal%20endoscopy,%2C%20diverticular%20disease%2C%20or%20cancer.

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