Immunodeficiency Caused by Viruses
DOI:
https://doi.org/10.47611/jsrhs.v13i2.6615Keywords:
Immunodeficiency, Viruses, Viral Proteins, HIV/AIDS, Immune System, Mononegavirales, Epithelial Cells, CD4-T Cells, Viral Spikes, Viral Attachment Proteins, Apoptosis, Antibodies, Monoclonal AntibodiesAbstract
Immunodeficiency is caused by many factors. One of these factors is viral transmission. Viruses like HIV, Ebola, and Measles have plagued humanity for decades, but why are they so significant? These viruses have different proteins on their membranes or envelopes that guide them to a specific host cell so they can replicate efficiently. In this process, cells die due to viral-induced apoptosis and therefore affect the body system that the cells are a part of. In these viruses’ case, they affect the immune system by directly replicating in immune cells or affecting cells which results in secondary infections and diseases. HIV (Human Immunodeficiency Virus) has proteins which guide it to CD4-T cells, a vital part of the immune system which triggers immune responses in the body. Other viruses such as Measles, Rabies, and Ebola are guided to epithelial cells, which are cells that line the organs and skin of the body. This makes the host vulnerable to secondary infections and diseases. Understanding these viruses is vital to improve current treatments for them and therefore improve society.
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