Implications of Chemotherapy, Radiation therapy, and Surgical treatment in Oral Cancer

Authors

  • Neha Tadikamalla Saratoga High School

DOI:

https://doi.org/10.47611/jsrhs.v13i2.6548

Keywords:

Oral Caner, Radiation Therapy, Chemotherapy, Surgery, Immunotherapy, Gene Therapy

Abstract

Oral cancer includes both the cancers of the mouth and back of the throat. This literature review investigates viable treatment modalities for adult patients diagnosed with oral cancer including the comparison of chemo/radiation therapy, surgery, and new treatment modalities. Surgical interventions are often the initial treatment, depending on tumor characteristics, and may require reconstructive procedures. Chemotherapy and radiation therapy, while effective, present challenges such as side effects such as nausea, vomiting, hair loss, and fatigue. With surgery, there is the consideration of different types of therapies. Post-operative care, lifestyle implications, and treatment success vary among these modalities. New treatments such as gene therapy and immunotherapy are also starting to appear. Findings suggest the drawbacks and the advantages of different treatments and possible preventive measures.

Downloads

Download data is not yet available.

References or Bibliography

Andreadis, Charalambos, et al. “5-Fluorouracil and Cisplatin in the Treatment of Advanced Oral Cancer.” Oral Oncology, vol. 39, no. 4, Elsevier BV, June 2003, pp. 380–85. https://doi.org/10.1016/s1368-8375(02)00141-0.

Bagán, José, et al. “Oral Cancer: Clinical Features.” Oral Oncology, vol. 46, no. 6, Elsevier BV, June 2010, pp. 414–17. https://doi.org/10.1016/j.oraloncology.2010.03.009.

“Chemotherapy Side Effects.” American Cancer Society, www.cancer.org/cancer/managing-cancer/treatment-types/chemotherapy/chemotherapy-side-effects.html.

“Chemotherapy to Treat Cancer.” National Cancer Institute, 23 Aug. 2022, www.cancer.gov/about-cancer/treatment/types/chemotherapy.

Kademani, Deepak. “Oral Cancer.” Mayo Clinic Proceedings, vol. 82, no. 7, Elsevier BV, July 2007, pp. 878–87. https://doi.org/10.4065/82.7.878.

Lingen, Mark W., et al. “Critical Evaluation of Diagnostic Aids for the Detection of Oral Cancer.” Oral Oncology, vol. 44, no. 1, Elsevier BV, Jan. 2008, pp. 10–22. https://doi.org/10.1016/j.oraloncology.2007.06.011.

Mullen, Matthew G., et al. “Risk Associated With Complications and Mortality After Urgent Surgery Vs Elective and Emergency Surgery.” JAMA Surgery, vol. 152, no. 8, American Medical Association, Aug. 2017, p. 768. https://doi.org/10.1001/jamasurg.2017.0918.

Nandini, Db, et al. “Novel Therapies in the Management of Oral Cancer: An Update.” Disease-a-Month, vol. 66, no. 12, Elsevier BV, Dec. 2020, p. 101036. https://doi.org/10.1016/j.disamonth.2020.101036.

Osman, Nemer, et al. “Weekly Cisplatin Concurrently With Radiotherapy in Head and Neck Squamous Cell Cancer: A Retrospective Analysis of a Tertiary Institute Experience.” European Archives of Oto-rhino-laryngology, vol. 271, no. 8, Springer Science+Business Media, Oct. 2013, pp. 2253–59. https://doi.org/10.1007/s00405-013-2749-9.

Pietrangelo, Ann. “The Value and Cost of Immunotherapy Cancer Treatments.” Healthline, 18 Oct. 2016, 11. www.healthline.com/health-news/value-and-cost-of-immunotherapy#The-problem-of-cost.

Shah, Jatin P., and Ziv Gil. “Current Concepts in Management of Oral Cancer – Surgery.” Oral Oncology, vol. 45, no. 4–5, Elsevier BV, Apr. 2009, pp. 394–401. https://doi.org/10.1016/j.oraloncology.2008.05.017.

“Surgery for Oral (Mouth) and Oropharyngeal (Throat) Cancer.” American Cancer Society, www.cancer.org/cancer/oral-cavity-and-oropharyngeal-cancer/treating/surgery.html.

“---.” American Cancer Society, www.cancer.org/cancer/types/oral-cavity-and-oropharyngeal-cancer/treating/surgery.html

Times, New York. “‘More Than Human.’” The New York Times, 3 July 2005, www.nytimes.com/2005/07/03/books/chapters/more-than-human.html.

“What Is Chemotherapy? | Chemo Treatment for Cancer.” American Cancer Society, www.cancer.org/treatment/treatments-and-side-effects/treatment-types/chemotherapy.html.

“What Is Immunotherapy? | Immunotherapy for Cancer.” American Cancer Society, www.cancer.org/cancer/managing-cancer/treatment-types/immunotherapy.html.

Published

05-31-2024

How to Cite

Tadikamalla, N. (2024). Implications of Chemotherapy, Radiation therapy, and Surgical treatment in Oral Cancer. Journal of Student Research, 13(2). https://doi.org/10.47611/jsrhs.v13i2.6548

Issue

Section

HS Review Articles