Antimicrobial Resistance and Molecular Interaction with Drugs
DOI:
https://doi.org/10.47611/jsrhs.v12i4.5894Keywords:
Antimicrobial Resistance, Molecular Level, SolutionsAbstract
Recently, people have been tackling a new problem in healthcare: antimicrobial resistance. Due to drug use (more specifically, drug misuse) in the previous years, bacteria have developed a resistance to modern drugs. Antimicrobial resistance makes current drugs less helpful in fighting certain types of bacteria. This study navigates on the description of antimicrobial resistance, its effects, and its solutions. Understanding Antimicrobial Resistance reveals mechanisms that microorganisms employ to render antimicrobial agents impotent. Understanding this knowledge can help make drugs more effective not only in the present but also in the future. Factors influencing antimicrobial resistance, including antibiotic misuse and horizontal gene transfer, reveal insights into the evolutionary arms race between microbes and drugs. Exploring molecular interactions between organisms and drugs can reveal the complex relationship between antimicrobial agents and pathogens. Consequences of antimicrobial resistance and strategies to combat antimicrobial resistance is another aspect that assesses the impact on patient outcomes, healthcare expenditure, and societal well-being. Approaches in drug development are from the topics of genomics, proteomics, and structural biology to increase the effectiveness of drugs. In conclusion, understanding the relationship between drugs and microorganisms lays the foundation for innovative drug development and strategies to preserve antimicrobial efficacy. Understanding this knowledge will not only help us now but will safeguard the role of drugs in the future.
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Copyright (c) 2023 Sridhar Alagar Ramanujam; Dr. Rajagopal Appavu, Jothsna Kethar
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