Evaluation of the Potential for Curcumin from Turmeric to be Used Against Pathogenic Bacteria
DOI:
https://doi.org/10.47611/jsrhs.v12i4.5851Keywords:
Curcumin, Turmeric, Bacteria, Pathogenic Bacteria, Bactericidal, Alternative MedicineAbstract
Turmeric is a natural product used for centuries in alternative medicine in various cultures around the world. It is a multi-faceted natural remedy that may assist in combating a variety of microbial threats, harboring an impressive array of health-promoting properties. Turmeric is recognized to have bacterial properties as this spice has an active ingredient curcumin with anti-inflammatory, anticancer, and antioxidant benefits. This bioactive compound has been the focus of extensive scientific research for this reason. Among its many beneficial attributes, curcumin stands out for its potential as a natural antibacterial agent, effectively combating common pathogens including both gram-positive and gram-negative bacteria, as well as MRSAs. This study reveals that the curcumin from turmeric is effective to be used in clinical settings against pathogenic bacteria, as it has many bactericidal properties which are proven to be equal, if not more effective than that of our modern day antibiotics. A challenge seen with the usage of curcumin would be its low bioavailability due to its solubility. In order to counter this, there are various methods involving transforming the chemical into a different form called nanocurcumin. As an antibiotic, it works by using cell wall damaging mechanisms in order to be an bactericidal agent. Further studies are needed to determine the appropriate dosages, formulations, and safety profiles for using curcumin as an antibiotic in clinical settings for humans.
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