Environmental & genetic factors and depression
DOI:
https://doi.org/10.47611/jsrhs.v12i2.4254Keywords:
Depression, Environmental factor; Genetic Factor, InterventionsAbstract
As reported by the World Health Organization (WHO) in 2021, depression is prevalent among ~3.8% of the world population, and it is impacting people’s life in many negative ways including effects such as lack of motivation, low mood, suicidal thoughts and acts, etc. Such extensive influence involves various triggers and causes --- environmental factors like childhood trauma, early-life experience, diet, etc. --- which could also lead to malfunction and structural change in certain brain areas like ACC and amygdala; Genetic factor is linked with the inherited genes with specific SNPs of individuals, in which the sequencing associated with depression is noticed by GWAS study. Common intervention strategies include taking antidepressants and doing mindfulness-based interventions to treat depressions are also being looked at in this paper.
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References or Bibliography
Agius, M., & Bonnici, H. (2017). Antidepressants in use in clinical practice (Vol. 29). Psychiatria Danubina.
Disner, S. G., Beevers, C. G., & Haigh, E. (2011). Neural mechanisms of the cognitive model of depression (Vol. 12). Nature Reviews.
Firth, J., Stubbs, B., & Teasdale, S. B. (2018). Diet as a hot topic in psychiatry: A population-scale study of nutritional intake and inflammatory potential in severe mental illness. In J. Firth, B. Stubbs, & S. B. Teasdale (Authors), Diet as a hot topic in psychiatry: A population-scale study of nutritional intake and inflammatory potential in severe mental illness. World Psychiatry.
Heim, C., Mayberg, H., Mletzko, T., Nemeroff, C., & JC, P. (2013). Decreased cortical representation of genital somatosensory field after childhood sexual abuse. Am. J. Psychiatr.
Herzog, J. I., & Schmahl, C. (2018). Adverse childhood experiences and the consequences on neurobiological, psychosocial, and somatic conditions across the lifespan (J. Lindert, Ed.; Vol. 9). Frontiers in Psychiatry.
Hofmann, S. G., & Gómez, A. F. (2018). Mindfulness-based interventions for anxiety and depression. Psychiatr Clin North Am.
LeMoult, J., Humphreys, K. L., Tracy, A., & Hoffmeister, J.-A. (2020). Meta-analysis: Exposure to early life stress and risk for depression in childhood and adolescence (Vol. 59). Journal of the American Academy of Child & Adolescent Psychiatry.
Liao, Y., Xie, B., Zhang, H., He, Q., Guo, L., & Subramaniapillai, M. (2021). Correction: Efficacy of omega-3 PUFAs in depression: A meta-analysis. Translational Psychiatry.
Lupien, S., Parent, S., Evans, A., Tremblay, R., & Zelazo, P. (2011). Larger amygdala but no change in hippocampal volume in 10-year-old children exposed to maternal depressive symptomatology since birth. Proc Natl Acad Sci USA.
Marx, W., Lane, M., & Aslam, H. (2020). Diet and depression: Exploring the biological mechanisms of action. Springer Nature.
Mullins, N., & Lewis, C. M. (2017). Genetics of depression: Progress at last. In Genetics of depression: Progress at last. Springer.
N, C., TB, B., KretzschmarWW, Li, Y., Liang, J., & Hu, J. (2017). 670 whole-genome sequences representative of the Han Chinese population from the CONVERGE project. Sci Data.
Ripke, S., Wray, N., Lewis, C., Hamilton, S., & WeissmanMM. (2013). A mega-analysis of genome-wide association studies for major depressive disorder. Mol Psychiatry.
Schulze, L., Schmahl, C., & Niedtfeld, I. (2016). Neural correlates of disturbed emotion processing in borderline personality disorder: A multimodal meta-analysis. Biol Psychiatr.
Vermetten, E., Schmahl, C., Lindne, S., Loewenstein, R., & Bremner, J. (2006). Hippocampal and amygdalar volumes in dissociative identity disorder. Am J Psychiatr.
Whittle, S., Dennison, M., Vijayakumar, N., Simmons, J., Yucel, M., & Lubman, D. (2013). Childhood maltreatment and psychopathology affect brain development during adolescence. J Am Acad Child Adolesc Psychiatr.
Yahfoufi, N., Alsadi, N., Jambi, M., & Matar, C. (2018). The immunomodulatory and anti-Inflammatory role of polyphenols. Nutrients.
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