Brain, Memory, and Amnesia

Authors

  • Ryan Zhang Sycamore High School
  • Thomas Andl University of Central Florida

DOI:

https://doi.org/10.47611/jsrhs.v11i3.3239

Keywords:

Brain, Memory, Amnesia, Memory loss

Abstract

Amnesia is a large-scale and long-term memory loss. Complications of amnesia, including the inability to create new memories and learn new things, severely reduce the quality of an individual's life. In the last three centuries, many famous clinical studies, including the one involving Henry Molaison (H.M), have been completed, furthering our understanding of the brain’s memory system and amnesia. Especially, a variety of psychological and neurological causes of amnesia have been identified. Different treatments are available for different types of amnesia; however, due to the extensive causes of amnesia, finding a common cure has proven to be difficult. This review will focus on our current understanding of the memory system and history of amnesia as well as the types, causes, preventive measures, and potential treatment strategies of amnesia.

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Author Biography

Thomas Andl, University of Central Florida

Advisor

References or Bibliography

Alberini, C. M., & Travaglia, A. (2017). Infantile amnesia: A critical period of learning to learn and remember. The Journal of Neuroscience, 37(24), 5783–5795. https://doi.org/10.1523/jneurosci.0324-17.2017

Allen, R. J. (2018). Classic and recent advances in Understanding amnesia. F1000Research, 7, 331. https://doi.org/10.12688/f1000research.13737.1

Alzheimer's Association. (n.d.). Korsakoff syndrome. Alzheimer's Disease and Dementia. https://www.alz.org/alzheimers-dementia/what-is-dementia/types-of-dementia/korsakoff-syndrome

American Psychological Association. (2017, July 31). Eye movement desensitization and reprocessing (EMDR) therapy.

American Psychological Association. https://www.apa.org/ptsd-guideline/treatments/eye-movement-reprocessing

Anand, K. S., & Dhikav, V. (2012). Hippocampus in health and disease: An overview. Annals of Indian Academy of Neurology, 15(4), 239. https://doi.org/10.4103/0972-2327.104323

Anderson, A. (2022, April 28). What is infantile amnesia? WebMD. https://www.webmd.com/children/what-is-infantile-amnesia

Baxter, M. G., & Croxson, P. L. (2012). Facing the role of the amygdala in emotional information processing. Proceedings of the National Academy of Sciences, 109(52), 21180–21181. https://doi.org/10.1073/pnas.1219167110

Bennett, C. (2019, March 6). What is the neocortex? News - Medical Life Sciences. https://www.news-medical.net/health/What-is-the-Neocortex.aspx

Berkheiser, K. (2018, June 14). 9 health benefits of Vitamin B12, based on science. Healthline. https://www.healthline.com/nutrition/vitamin-b12-benefits

Cherry, K. (2022, May 20). What is Episodic Memory. Verywell Mind. https://www.verywellmind.com/what-is-episodic-memory-2795173#:~:text=Episodic%20vs.,-Semantic%20Memory&text=Semantic%20memory%20is%20focused%20on,as%20explicit%20or%20declarative%20memory

Cleveland Clinic. (2020). Dissociative amnesia: Symptoms, causes, Management & Treatment. Cleveland Clinic. https://my.clevelandclinic.org/health/diseases/9789-dissociative-amnesia

Cleveland Clinic. (2020, August 10). PET scan: Tests, types, procedure. Cleveland Clinic. https://my.clevelandclinic.org/health/diagnostics/10123-pet-scan

Corkin, S. (2002). What's new with the amnesic patient H.M.? Nature Reviews Neuroscience, 3(2), 153–160. https://doi.org/10.1038/nrn726

Corkin, S., Amaral, D. G., González, R. G., Johnson, K. A., & Hyman, B. T. (1997). H. M.’s medial temporal lobe lesion: Findings from Magnetic Resonance Imaging. The Journal of Neuroscience, 17(10), 3964–3979. https://doi.org/10.1523/jneurosci.17-10-03964.1997

Covington, N. V., & Duff, M. C. (2018, September 6). Amnesia and the multiple memory systems of the brain. Frontiers for Young Minds. https://kids.frontiersin.org/articles/10.3389/frym.2018.00045

Cowan, N. (2013). Working memory underpins cognitive development, learning, and Education. Educational Psychology Review, 26(2), 197–223. https://doi.org/10.1007/s10648-013-9246-y

D’Ardenne, K., Eshel, N., Luka, J., Lenartowicz, A., Nystrom, L. E., & Cohen, J. D. (2012). Role of prefrontal cortex and the midbrain dopamine system in working memory updating. Proceedings of the National Academy of Sciences, 109(49), 19900–19909. https://doi.org/10.1073/pnas.1116727109

Davis, K. (2022, March 24). Cognitive behavioral therapy: How does CBT work? Medical News Today. https://www.medicalnewstoday.com/articles/296579

Esther Heerema, M. S. W. (2022, February 17). 4 types of memory that everyone has. Verywell Health. https://www.verywellhealth.com/types-of-memory-explained-98552

Gibson, M., & Malik, Z. (Eds.). (2021). Amnesia Epidemiology and demographics. wikidoc. https://www.wikidoc.org/index.php/Amnesia_epidemiology_and_demographics#:~:text=Prevalence,dissociative%20fugue%20is%20approximately%200.2%25

Godman, H. (2014, April 9). Regular exercise changes the brain to improve memory, thinking skills. Harvard Health. https://www.health.harvard.edu/blog/regular-exercise-changes-brain-improve-memory-thinking-skills-201404097110

Gropper, M. (2020). Implicit Memory. Implicit Memory - an overview | ScienceDirect Topics. https://www.sciencedirect.com/topics/neuroscience/implicit-memory#:~:text=Implicit%20memory%2C%20often%20referred%20to,involves%20the%20process%20of%20priming

Guy-Evans, O. (2021, April 12). Cerebellum functions, structure, and location. Cerebellum: Functions, Structure, and Location | Simply Psychology. https://www.simplypsychology.org/what-is-the-cerebellum.html

Harrison, N. A., Johnston, K., Corno, F., Casey, S. J., Friedner, K., Humphreys, K., Jaldow, E. J., Pitkanen, M., & Kopelman, M. D. (2017, August 24). Psychogenic amnesia: Syndromes, outcome, and patterns of Retrograde amnesia. OUP Academic. https://academic.oup.com/brain/article/140/9/2498/4080831

Headway. (n.d.). How severe is the brain injury? Headway.

https://www.headway.org.uk/about-brain-injury/individuals/types-of-brain-injury/traumatic-brain-injury/how-severe-is-the-brain-injury/

Headway. (n.d.). Post-traumatic amnesia. Headway.

https://www.headway.org.uk/about-brain-injury/individuals/effects-of-brain-injury/post-traumatic-amnesia/

Heaning, E. (2022, January 13). Henry Gustav Molaison. Henry Gustav Molaison (Patient H.M.) - Simply Psychology. https://www.simplypsychology.org/henry-molaison-patient-hm.html#:~:text=For%20starters%2C%20H.M%20suffered%20from,current%20research%20theorizes%20that%20H

Heller, L. (2015, October 5). Korsakoff's syndrome. Johns Hopkins Memory Disorders Center. Retrieved 2022, from https://www.hopkinsmedicine.org/neurology_neurosurgery/centers_clinics/memory_disorders/conditions/korsakoffs_syndrome.html

IAEA. (2016, April 13). Radiotracers. IAEA. https://www.iaea.org/topics/radiotracers

Kumar, K. (2021, April 21). What does it mean to have retrograde amnesia? MedicineNet. https://www.medicinenet.com/what_does_it_mean_to_have_retrograde_/article.htm

Kurlowicz, L. (1999, January). The Mini Mental State Examination (MMSE). The Hartford Institute For Geriatric Nursing. https://cgatoolkit.ca/Uploads/ContentDocuments/MMSE.pdf

Lanciego, J. L., Luquin, N., & Obeso, J. A. (2012). Functional neuroanatomy of the basal ganglia. Cold Spring Harbor Perspectives in Medicine, 2(12). https://doi.org/10.1101/cshperspect.a009621

Langer, K. G. (2021, June 10). The history of amnesia-a review - current neurology and Neuroscience Reports. SpringerLink. https://link.springer.com/article/10.1007/s11910-021-01126-x

Leong, S., Waits, W., & Diebold, C. (2006). Dissociative Amnesia and DSM-IV-TR Cluster C Personality Traits. Psychiatry (Edgmont (Pa. : Township)), 3(1), 51–55.

Magnetic Resonance Imaging (MRI). Johns Hopkins Medicine. (2021, December 6). https://www.hopkinsmedicine.org/health/treatment-tests-and-therapies/magnetic-resonance-imaging-mri#:~:text=What%20is%20MRI%3F,large%20magnet%20and%20radio%20waves

Mandal, D. A. (2019, January 22). Diagnosis of amnesia. News - Medical Life Sciences.

https://www.news-medical.net/health/Diagnosis-of-amnesia.aspx

Marzbani, H., Marateb, H. R., & Mansourian, M. (2016, April). Neurofeedback: A comprehensive review on system design, methodology and clinical applications. Basic and clinical neuroscience. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892319/

Mayo Foundation for Medical Education and Research. (2020, September 15). Amnesia. Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/amnesia/diagnosis-treatment/drc-20353366

Mayo Foundation for Medical Education and Research. (2022, August 10). Transient global amnesia. Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/transient-global-amnesia/symptoms-causes/syc-20378531#:~:text=Transient%20global%20amnesia%20is%20a,or%20how%20you%20got%20there

Mayo Foundation for Medical Education and Research. (2022, May 11). EEG (electroencephalogram). Mayo Clinic. https://www.mayoclinic.org/tests-procedures/eeg/about/pac-20393875

Nehring, S. M., Spurling, B. C., & Kumar, A. (n.d.). Transient global amnesia - statpearls - NCBI bookshelf. Retrieved https://www.ncbi.nlm.nih.gov/books/NBK442001/

NYU Langone Health. (n.d.). Diagnosing memory loss. Patient Care at NYU Langone Health. Retrieved 2022, from https://nyulangone.org/conditions/memory-loss-in-adults/diagnosis

Pinto, *C., Hodawadekar, A., Hatle, V., & Kanekar, A. (2021, August 24). A Review To Understand Excelsior Advances And Innovative Diagnosis Of Amnesia. World Journal of Pharmaceutical Research https://wjpr.net/abstract_file/17551

Ratini, M. (2019, May 19). Amnesia: Types, causes, treatment, and more. WebMD. https://www.webmd.com/brain/what-to-know-about-amnesia

Smith, C. N., Frascino, J. C., Hopkins, R. O., & Squire, L. R. (2013). The nature of anterograde and retrograde memory impairment after damage to the medial temporal lobe. Neuropsychologia, 51(13), 2709–2714. https://doi.org/10.1016/j.neuropsychologia.2013.09.015

Rosenbaum, R. S., Murphy, K. J., & Rich, J. B. (2011). The amnesias. Wiley Interdisciplinary Reviews: Cognitive Science, 3(1), 47–63. https://doi.org/10.1002/wcs.155

Smith, C. N., Frascino, J. C., Hopkins, R. O., & Squire, L. R. (2013). The nature of anterograde and retrograde memory impairment after damage to the medial temporal lobe. Neuropsychologia, 51(13), 2709–2714. https://doi.org/10.1016/j.neuropsychologia.2013.09.015

Squire, L. R. (2009). The legacy of patient H.M. for Neuroscience. Neuron, 61(1), 6–9. https://doi.org/10.1016/j.neuron.2008.12.023

Vitelli, R. (2014, April 14). Exploring childhood amnesia. Psychology Today. https://www.psychologytoday.com/us/blog/media-spotlight/201404/exploring-childhood-amnesia

Where are memories stored in the brain? Queensland Brain Institute - University of Queensland. (2018, July 23). https://qbi.uq.edu.au/brain-basics/memory/where-are-memories-stored

Published

08-31-2022

How to Cite

Zhang, R., & Andl, T. (2022). Brain, Memory, and Amnesia. Journal of Student Research, 11(3). https://doi.org/10.47611/jsrhs.v11i3.3239

Issue

Section

HS Review Articles