Mutations In Influenza Viruses and Prevention Against These Viruses

Authors

  • Rohit Rao Central Bucks High School South
  • Rajagopal Appavu Appavu Gifted Gabber
  • Jothsna Kethar Gifted Gabber

DOI:

https://doi.org/10.47611/jsrhs.v11i2.2568

Keywords:

Influenza, Influenza Virus, Virus, CRISPR, Mutations, Mutations in Influenza Virus

Abstract

The flu originated in 1918 and started a pandemic that spread around the world, killing millions. Other than the current COVID-19 pandemic, the Flu Pandemic of the late 1910s and early 1920s has killed and infected more people than any other virus in modern world history. Since then, the flu has become a seasonal virus that has predictable times of infections. Due to modern medicine, most people are able to survive such infections, and continue on with their lives with little impact. However, as you might come to wonder either eventually or even right now, a person may be curious behind why such an “outdated virus” still continues to live on every winter season. This paper will research the mechanisms of such processes that allow these viruses to stay “alive” (because they technically are not a living thing) and prevent themselves from being eradicated by today’s medical technology. We also look into common and new preventions/ treatments that is/ can be used to eventually eradicate the flu.

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Author Biographies

Rohit Rao, Central Bucks High School South

warrington, PA. USA

 

Rajagopal Appavu Appavu, Gifted Gabber

Advisor

Jothsna Kethar, Gifted Gabber

Advisor

References or Bibliography

Cann, A. (2008). Replication of Viruses. Encyclopedia of Virology, 406–412. https://doi.org/10.1016/b978-012374410-4.00486-6

Central Dogma of Biology: Classic View. (2007). National Center for Biotechnology Information, 1. https://www.ncbi.nlm.nih.gov/Class/MLACourse/Modules/MolBioReview/central_dogma.html

The Central Dogma of Genetics. (n.d.). [Illustration]. Exploring Nature. https://www.exploringnature.org/graphics/genome_art/central_dogma72.jpg

Chandra, K. C. (n.d.). Structure of influenza viruses [Illustration]. EazzyNotes. https://i0.wp.com/eazzynotes.com/wp-content/uploads/2020/04/influenzaviruslabeled-scaled.jpg?resize=768%2C503&ssl=1

Collins, F. (2021). CRISPR-Based Anti-Viral Therapy Could One Day Foil the Flu—and COVID-19. NIH Director’s Blog. https://directorsblog.nih.gov/2021/03/16/crispr-based-anti-viral-therapy-could-one-day-foil-the-flu-and-covid-19/

Grubaugh, N. et al. (2020). We shouldn’t worry when a virus mutates during disease outbreaks. Nature Microbiology, 5(4), 529–530. https://doi.org/10.1038/s41564-020-0690-4

How Flu Viruses Can Change. (2021, September 21). Centers for Disease Control and Prevention. Retrieved September 21, 2021, from https://www.cdc.gov/flu/about/viruses/change.htm

Influenza Milestones 1917 – 2009 Timeline | Pandemic Influenza (Flu) | CDC. (n.d.). Centers for Disease Control and Prevention. Retrieved March 22, 2018, from https://www.cdc.gov/flu/pandemic-resources/1918-commemoration/milestone-infographic.htm

McNeil, T. M. (2021, August 20). How Viruses Mutate and Create New Variants. Tufts Now. Retrieved January 8, 2022, from https://now.tufts.edu/articles/how-viruses-mutate-and-create-new-variants

Past Seasons Estimated Influenza Disease Burden | CDC. (n.d.). Centers for Disease Control and Prevention. Retrieved October 1, 2020, from https://www.cdc.gov/flu/about/burden/past-seasons.html

Percentage of visits for influenza- like illness (ILI) reported by the U.S. outpatient influenza-like illness surveillance network (ILINet), weekly national summary, september 28, 2008 - november 12, 2011). (n.d.). [Graph]. Centers for Disease Control and Prevention. https://www.cdc.gov/flu/weekly/weeklyarchives2011-2012/images/picILI45.GIF

Sanjuán, R. et al. (2016). Mechanisms of viral mutation. Cellular and Molecular Life Sciences, 73(23), 4433–4448. https://doi.org/10.1007/s00018-016-2299-6

Vaccine Effectiveness: How Well Do Flu Vaccines Work? | CDC. (2021, October 25). Centers for Disease Control and Prevention. https://www.cdc.gov/flu/vaccines-work/vaccineeffect.htm

What is CRISPR? (n.d.). [Illustration]. Absolute Knowledge. https://www.absolute-knowledge.com/wp-content/uploads/2018/04/CRISPR.jpg

Published

05-31-2022

How to Cite

Rao, R., Appavu, R. A., & Kethar, J. (2022). Mutations In Influenza Viruses and Prevention Against These Viruses. Journal of Student Research, 11(2). https://doi.org/10.47611/jsrhs.v11i2.2568

Issue

Section

HS Research Articles