Analyzing Toxicology Reports of the COVID-19 Vaccine
DOI:
https://doi.org/10.47611/jsrhs.v10i4.1996Keywords:
toxicology, Covid-19, Vaccine, Recombinant vaccines, mRNA vaccines, Live-attenuated vaccines, Inactivated vaccinesAbstract
In the development of vaccines for treatment against SARS-CoV-2, several categories have emerged and their benefits and concerns have become apparent. An ideal target, the Spike (S) protein, has emerged and become the focus of recombinant vaccines. The S protein is crucial for the infection process of SARS-CoV-2. Recombinant vaccines make use of this and focus on creating an immune response targeting the S protein. There are various subcategories of recombinant vaccines and all function in a fundamentally similar manner. Two other types of vaccines are live-attenuated and inactivated vaccines. They utilize weakened or inactivated coronavirus to create an immune response, unlike recombinant vaccines. Nucleic acid-based coronavirus vaccines are a subcategory of recombinant vaccines and include DNA- and RNA-based vaccines. Recombinant vaccines make full use of the presented target and efficiently provide superior treatment against SARS-CoV-2.
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References or Bibliography
AstraZeneca ChAdOx1-S/nCoV-19 [recombinant], COVID-19 vaccine. (2021).Â
Benedette Cuffari, M. (2021). What are Spike Proteins?. Retrieved 29 July 2021
Everything You Need to Know About Coronavirus - Berkeley Lights. (2020). https://www.berkeleylights.com/blog/everything-you-need-know-about-coronavirus/
Pollet, J., Chen, W., & Strych, U. (2020). Recombinant Protein Vaccines, a Proven Approach Against Coronavirus Pandemics. Retrieved 29 July 2021, from https://www.preprints.org/manuscript/202011.0558/v1
Understanding How COVID-19 Vaccines Work. (2021). Retrieved 29 July 2021, from https://www.cdc.gov/coronavirus/2019-ncov/vaccines/different-vaccines/how-they-work.html#:~:text=COVID%2D19%20vaccines%20help,to%20get%20the%20illness
Vaccine Types. (2021). Retrieved 29 July 2021, from https://www.hhs.gov/immunization/basics/types/index.html
Yadav, T., Srivastava, N., Mishra, G., Dhama, K., Kumar, S., Puri, B., & Saxena, S. (2021). Recombinant vaccines for COVID-19. Retrieved 29 July 2021, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711739/
Zhang, N., Li, X., Deng, Y., Zhao, H., Huang, Y., & Yang, G. et al. (2020). A Thermostable mRNA Vaccine against COVID-19. Retrieved 29 July 2021, from https://www.sciencedirect.com/science/article/abs/pii/S0092867420309326
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Copyright (c) 2021 Eesha Lingala; Dr. Rajagopal Appavu, Jothsna Kethar
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